Research Core Charter

Research Core Charter

This charter document delineates the GEAR 2.0 ADC Research Core Group project purpose, goals, and participant expectation

I) Purpose and Goals

GEAR 2.0 ADC Description

A fully integrated research and resource network comprised of experts in emergency medicine, geriatrics and Alzheimer’s Disease and related dementias (ADRD) that identifies research and practice gaps in the emergency care of people living with dementia (PLWD) and establishes strategies to resolve these gaps.

GEAR 2.0 ADC Goals

To develop collaborations, resources, and research infrastructure to foster transdisciplinary researchers in the emergency care of older adults with ADRD and their caregivers.

Phase 1 Aims (R61): Identify and propose strategies to address research gaps. Establish the GEAR 2.0 ADC infrastructure. (Yr 1-2)
  1. Determine research priorities for ED care of PLWD and their caregivers using a consensus process in four domains: 1. ED practices, 2. ED care transitions, 3. Detection, and 4. Communication and decision making.
  2. Determine the strength of available evidence by systematically conducting scoping reviews.
  3. Prioritize research and practice gaps in emergency care for PLWD by convening a transdisciplinary stakeholder taskforce meeting.
  4. Establish GEAR 2.0 – ADC governance and operations to support R33 pilot studies by partnering and leveraging transdisciplinary networks and organizations: including GEDC, ADRCs, and GEAR 2.0 Cores: 1. Administrative, 2. Research, 3. Data/Informatics, and 4. Dissemination & Implementation.
Phase 2 Aims (R33): Support research strategies. (Yr 3-5)
  1. Solicit, review, select, and fund research that will lead to future full-scale proposals addressing research gaps in emergency care for PLWD and their care partners.
  2. Deploy resources to support collaborative emergency care dementia research.

Project Successfully Complete When:

GEAR 2.0 ADC is considered impactful if it expands research optimizing the emergency care and health of PLWD and their care partners. Success is determined by pilot studies transitioning to full-scale funded projects or by expanding the collaborative network.

II) Research Core Purpose and Goals

Research Core Description

The Research Core will support pilot grantees to successfully navigate methodological challenges in conducting emergency care research among PLWD. It has expertise and will provide training in geriatic emergency care, cohort studies and clinical trials, assessment of neurological and behavior function assessments, recruitment and retention in studies of PLWD, and adaptation of study design and analytic methods towards the specific study populations, setting, and research questions

Research Core Specific Aims

This core is important to address the many unique aspects of research in the ED and with PLWD. The Research Core will support GEAR 2.0 pilot studies in the following specific ways:
  1. Supporting the Admin Core and its education programs to train researchers, including webinars.
    • a) Create presentations for webinars tailored to grantees needs.
    • b) Create Podcasts in conjunction with the grantees.
  2. Providing consultations to grantees on research methods (e.g. inclusion criteria, measures, design, randomization, strategies to prevent or reduce missing data, analysis plan)
    • a) Hold office hours at least once a month for the grantees to discuss research methods specific to their pilot projects.
  3. Posting materials on the GEAR 2.0 website that will include research reports, manuscripts, successful research proposals, and successful summary statements.
  4. Assisting grantees during the post-study transition period to identify and apply for larger scale funding.

Core Staff

Scott Dresden, MD, MS
GEAR 2.0 Co-Investigator
Northwestern University
s-dresden@northwestern.edu

Richard Marottoli, MD MPH
ADRC, Yale University
richard.marottoli@yale.edu

Heather Allore, PhD
Biostatistics, Yale University
heather.allore@yale.edu

Zachary Taylor, MPH
GEAR 2.0 Member
Northwestern University
zachary.taylor@northwestern.edu

William Hung, MD, MPH
Geriatrics, Mount Sinai
william.hung@mssm.edu

Manish Shah, MD MPH
GEAR 2.0-ADC PI Rep
University of Wisconsin – Madison
mnshah@medicine.wisc.edu

Responsibilities & Expectations

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